Support GLUT-4 and improve your metabolic health

To support GLUT-4 and improve metabolic health, the protocol should:

Stimulate muscle GLUT-4 translocation via movement (i.e. strength training, walking after meals).
Reduce inflammation, oxidative stress, and metabolic load (support liver, mitochondria, insulin sensitivity).
Balance hormones (estrogen, progesterone, cortisol, thyroid) since hormonal shifts in midlife strongly affect glucose regulation.
Support foundational nutrients that assist insulin signaling, glucose transport, and metabolic homeostasis.
Stabilize lifestyle factors: sleep, stress, gut health, meal timing, protein/ carb balance.

With that foundation, when paired with a supplement strategy, results tend to be more robust and sustainable.

Here are supplements that support GLUT-4 & metabolic protocol.

BERBERINE+
Supports insulin sensitivity, lipid metabolism, and glucose balance. Especially helpful when fasting or post-meal insulin or glucose runs high.

Myo-Inositol (Inositol+)
Well-supported for improving insulin sensitivity, glucose uptake, ovarian hormone balance, and metabolic health—especially helpful in metabolic syndrome and peri/postmenopause.

TRI . MAG
Magnesium supports insulin receptor sensitivity and GLUT-4 activation. Improves glucose transport and helps stabilize metabolic function.

MITO . BOOST
Enhances mitochondrial health, which improves cellular energy production. When mitochondria perform well, glucose uptake and metabolism also improve. Key for metabolic flexibility and preventing insulin resistance.

STRESS . ADAPT
Chronic stress and high cortisol impair insulin signaling and blunt GLUT-4 responsiveness. Adaptogens support more stable cortisol rhythms and better hormonal/metabolic balance.

High-Protein Intake + Creatine
Muscle is the biggest GLUT-4 reservoir. Strength training plus adequate protein—and optionally creatine—helps build and preserve muscle mass, improving insulin sensitivity and glucose clearance.