Why Artificial Sweeteners Are a Problem in Perimenopause
- Dr. Jen
- 4 days ago
- 1 min read

If you’ve been leaning on “zero-calorie” sweeteners like sucralose or acesulfame potassium (Ace-K), it might be time to rethink them—especially if you’re in perimenopause.
Here’s why:
They disrupt your gut microbiome.Sucralose and Ace-K reduce beneficial bacteria, worsening bloating, constipation, and hormone detox pathways that are already more sluggish in perimenopause.
They affect blood sugar and insulin.Even without calories, some women still experience insulin spikes. Since estrogen naturally supports insulin sensitivity, and estrogen is dropping in perimenopause, artificial sweeteners can make weight management even harder.
They confuse appetite regulation.Your brain tastes sweet, expects energy, but doesn’t get it → cravings increase. This cycle often backfires and leads to overeating.
They may disrupt hormones further.Preliminary research suggests they may impact thyroid and estrogen signaling. During perimenopause, when hormones are already fluctuating, this adds more instability.
They stress mitochondria.Studies suggest possible oxidative stress, which can worsen fatigue, brain fog, and muscle loss—symptoms many women are already experiencing.
What to Use Instead
🌿 Stevia and monk fruit are natural, gut-friendly alternatives.🍯 Whole food sweeteners like raw honey or maple syrup (in moderation) add trace minerals and polyphenols.
✅ The Bottom Line
Artificial sweeteners aren’t the shortcut they claim to be. For women in perimenopause, they can make hormone symptoms worse, not better.
That’s why in my new book, The Perimenopause Reset, I walk you through exactly how to use food, supplements, and lifestyle shifts to support your hormones during this season of life.
👉 Grab your copy here and start feeling like yourself again.

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